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Turk J Med Sci ; 51(3): 912-920, 2021 06 28.
Article in English | MEDLINE | ID: covidwho-945993

ABSTRACT

Background/aim: The aim of this descriptive article is to share the experience in Ege University, Turkey with favipiravir in the treatment of severe SARS-CoV-2 pneumonia. Materials and methods: This retrospective descriptive study included patients diagnosed with COVID-19 who presented with or developed severe pneumonia. Results: Forty patients who completed a full course (at least 5 days) of favipiravir were included in the study. At baseline, 30 (75%) patients required treatment for respiratory distress. Thirty-three patients (82.5%) were discharged from the hospital with full recovery, 6 patients (15%) died and 1 case (2.5%) was still at the intensive care unit (ICU) when this paper was written. Conclusion: This study provides relevant information for the treatment of COVID-19, suggesting that favipiravir was associated with significant clinical and laboratory improvements in the majority of the patients, is a safe drug with no serious side effects and would merit further investigation.


Subject(s)
Amides/therapeutic use , COVID-19 Drug Treatment , Intensive Care Units/statistics & numerical data , Pandemics , Pyrazines/therapeutic use , SARS-CoV-2 , Adult , Aged , Antiviral Agents/therapeutic use , COVID-19/epidemiology , Female , Follow-Up Studies , Humans , Male , Middle Aged , Retrospective Studies , Time Factors , Treatment Outcome , Turkey/epidemiology
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